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iPSC \u7d30\u80de\u5eab\u662f\u6e90\u81ea\u4eba\u7fa4\u4e2d\u6700\u5e38\u898b\u55ae\u500d\u578b\u7d14\u5408\u5b50\uff08homozygous haplotypes\uff09\u500b\u9ad4\uff0c\u4ee5\u5339\u914d\u4eba\u985e\u767d\u7d30\u80de\u6297\u539f\uff08HLA\uff09\u7cfb\u7d71\uff0c\u8a72\u7cfb\u7d71\u7de8\u78bc\u7d30\u80de\u8868\u9762\u5206\u5b50\u5c08\u9580\u7528\u65bc\u5c07\u6297\u539f\u80bd\u5448\u905e\u7d66T\u7d30\u80de\u4e0a\u7684\u53d7\u9ad4\u3002iPSC\u7d30\u80de\u5eab\u7684\u5efa\u7acb\u53ef\u4ee5\u63d0\u4f9b\u73fe\u6210\u7684iPSC\uff0c\u9019\u4e9biPSC\u8207\u9700\u8981\u7d30\u80de\u7642\u6cd5\u7684\u500b\u9ad4\u60a3\u8005\u5bc6\u5207\u5339\u914d\u3002<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.xelleratherapeutics.com\/wp-content\/uploads\/2024\/10\/iPSC-haplobank-tradcn-new-1012&#215;693-1.jpg&#8221; alt=&#8221;iPSC-haplobank&#8221; title_text=&#8221;iPSC-haplobank-tradcn-new-1012&#215;693&#8243; _builder_version=&#8221;4.14.8&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.14.8&#8243; _module_preset=&#8221;default&#8221; text_orientation=&#8221;justified&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>\u4e16\u754c\u5404\u5730\u5df2\u7d93\u5efa\u7acb\u4e86\u8a31\u591aiPSC\u7d30\u80de\u5eab\uff0c\u5305\u62ec\u7f8e\u570b\u3001\u65e5\u672c\u548c\u97d3\u570b\u3002\u512a\u57fa\u79d1\u6280\u8207\u8607\u683c\u862d\u570b\u5bb6\u8f38\u8840\u670d\u52d9\u4e2d\u5fc3\u548c\u611b\u4e01\u5821\u5927\u5b78\u7b49\u672c\u5730\u548c\u6d77\u5916\u6a5f\u69cb\u5408\u4f5c\uff0c\u5728\u9999\u6e2f\u555f\u52d5\u4e86\u7b2c\u4e00\u500biPSC\u7d30\u80de\u5eab\u9805\u76ee\u3002 <\/p>\n<p>The Global Alliance for iPSC Therapies\u662f\u4e00\u500b\u7d44\u7e54\u806f\u76df\uff0c\u5305\u62ec<a href=\"https:\/\/nyscf.org\/\">New York Stem Cell Foundation<\/a> (New York, USA)\u3001the <a href=\"https:\/\/ct.catapult.org.uk\/\">Cell and Gene Therapy Catapult <\/a>(London, UK)\u3001the <a href=\"https:\/\/www.ccrm.ca\/\">Centre for Commercial-ization of Regenerative Medicine<\/a> (Toronto, Canada)\u3001the Korean HLA-Typed iPSC Banking Initiative (Seoul, Korea)\u548cthe <a href=\"https:\/\/www.inserm.fr\/\">French Institute of Health and Medical Research<\/a> INSERM (Paris, \uff0cFrance)\uff0c\u5176\u76ee\u7684\u662f\u652f\u6301\u8a98\u5c0e\u6027\u591a\u529f\u80fd\u5e79\u7d30\u80de\u7642\u6cd5\u7684\u5be6\u65bd\u548c\u81e8\u5e8a\u61c9\u7528\uff0c\u4ee5\u9020\u798f\u5168\u7403\u60a3\u8005\u3002\u6709\u95dcGAiT\u7684\u66f4\u591a\u8cc7\u8a0a\uff0c\u8acb\u53c3\u95b1\u6700\u8fd1\u767c\u8868\u7684<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1873506120303378#:~:text=The%20Global%20Alliance%20of%20iPSC,induced%20pluripotent%20stem%20cells%20for\" target=\"_blank\" rel=\"noopener\">\u6587\u7ae0<\/a>\u3002 <\/p>\n<p>\u4f5c\u70baGAiT\u7684\u6210\u54e1\u5730\u5340\uff0c\u512a\u57fa\u7684iPSC\u751f\u7522\u65b9\u6cd5\u7b26\u5408GAiT\u6307\u5f15\u3002\u540c\u6642\uff0c\u6211\u5011\u7684iPSC\u751f\u7522\u6d41\u7a0b\u4e5f\u7b26\u5408FDA\u3001EMA\u548cPIC\/S\u7684\u76e3\u7ba1\u6307\u5f15\u3002 <\/p>\n<p><a href=\"https:\/\/www.xelleratherapeutics.com\/zh-hant\/%e8%81%af%e7%b9%ab%e6%88%91%e5%80%91\/\"><strong>\u806f\u7d61\u6211\u5011<\/strong><\/a>\u7372\u53d6\u66f4\u591a\u6709\u95dcR&amp;D \u4ee5\u53caGMP iPSC\u751f\u7522\u670d\u52d9\u548ciPSC\u7d30\u80de\u5eab\u7684\u66f4\u591a\u8a73\u7d30\u4fe1\u606f\u3002<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.xelleratherapeutics.com\/wp-content\/uploads\/2024\/10\/iPSC-iPS-cells-graph-tradcn-new-1200&#215;631-1.jpg&#8221; alt=&#8221;iPSC-iPS-cells-graph&#8221; title_text=&#8221;iPSC-iPS-cells-graph-tradcn-new-1200&#215;631&#8243; _builder_version=&#8221;4.14.8&#8243; _module_preset=&#8221;default&#8221; 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global_colors_info=&#8221;{}&#8221;]\u9593\u5145\u8cea\u5e79\u7d30\u80de\uff08MSCs\uff09\uff0c\u4e5f\u7a31\u70ba\u9593\u5145\u8cea\u57fa\u8cea\u7d30\u80de\uff0c\u662f\u4e00\u7a2e\u591a\u529f\u80fd\u6027\u6210\u9ad4\u5e79\u7d30\u80de\uff0c\u4e00\u822c\u5b58\u5728\u65bc\u81cd\u5e36\u3001\u9aa8\u9ad3\u548c\u8102\u80aa\u7b49\u7d44\u7e54\u4e2d\u3002\u9019\u4e9b\u7d30\u80de\u5177\u6709\u5f88\u9ad8\u7684\u81ea\u6211\u66f4\u65b0\u80fd\u529b\uff0c\u53ef\u4ee5\u5206\u5316\u6210\u591a\u7a2e\u7d30\u80de\u985e\u578b\uff0c\u5982\u9aa8\u7d30\u80de\u3001\u8edf\u9aa8\u7d30\u80de\u3001\u808c\u8089\u7d30\u80de\u3001\u8102\u80aa\u7d30\u80de\u3001\u809d\u7d30\u80de\u548c\u5176\u4ed6\u7d50\u7de0\u7d44\u7e54\u3002\u9593\u5145\u8cea\u5e79\u7d30\u80de\u6703\u5206\u6ccc\u8a31\u591a\u751f\u7269\u6d3b\u6027\u56e0\u5b50\uff0c\u9019\u4e9b\u56e0\u5b50\u53ef\u4ee5\u9032\u4e00\u6b65\u4fc3\u9032\u5176\u5728\u518d\u751f\u91ab\u5b78\u548c\u7d44\u7e54\u4fee\u5fa9\u4e2d\u7684\u61c9\u7528\uff0c\u5305\u62ec\u9aa8\u518d\u751f\u3001\u8edf\u9aa8\u4fee\u5fa9\u7b49\u3002<br \/>\n[\/et_pb_text][et_pb_text _builder_version=&#8221;4.14.8&#8243; _module_preset=&#8221;default&#8221; text_orientation=&#8221;justified&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u9593\u5145\u8cea\u5e79\u7d30\u80de\u9084\u6703\u7522\u751f\u514d\u75ab\u8abf\u7bc0\u5206\u5b50\uff0c\u53ef\u4ee5\u6291\u5236\u514d\u75ab\u7cfb\u7d71\u4e26\u7522\u751f\u6297\u708e\u4f5c\u7528\u3002\u9019\u4f7f\u5f97\u9593\u5145\u8cea\u5e79\u7d30\u80de\u53ef\u4f5c\u70ba\u514d\u75ab\u8010\u53d7\u5291\u7528\u65bc\u6cbb\u7642\u8a31\u591a\u9069\u61c9\u75c7\uff0c\u5305\u62ec\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\uff08GVHD\uff09\u3001\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u548c\u708e\u75c7\u6027\u75be\u75c5\uff08\u514b\u7f85\u6069\u75c5\u7b49\uff09\u3002 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