{"id":6028,"date":"2022-03-04T19:22:48","date_gmt":"2022-03-04T11:22:48","guid":{"rendered":"https:\/\/www.xelleratherapeutics.com\/%e6%8a%80%e8%a1%93\/"},"modified":"2024-11-20T07:23:26","modified_gmt":"2024-11-19T23:23:26","slug":"%e6%8a%80%e8%a1%93","status":"publish","type":"page","link":"https:\/\/www.xelleratherapeutics.com\/zh-hant\/%e6%8a%80%e8%a1%93\/","title":{"rendered":"\u6280\u8853"},"content":{"rendered":"

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\ntransduction
\n” module_id=”CART” _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.8″ _module_preset=”default” text_orientation=”justified” global_colors_info=”{}”]<\/p>\n

\u5d4c\u5408\u6297\u539f\u53d7\u9ad4T\u7d30\u80de\u7684\u751f\u7522<\/h1>\n

[\/et_pb_text][et_pb_text _builder_version=”4.14.8″ _module_preset=”default” text_orientation=”justified” global_colors_info=”{}”]<\/p>\n

\u5d4c\u5408\u6297\u539f\u53d7\u9ad4\uff08CAR\uff09T\u7d30\u80de\u7642\u6cd5\u662f\u4e00\u7a2e\u9769\u547d\u6027\u7684\u6297\u764c\u7642\u6cd5\u3002\u8fd1\u5e74\u56e0CAR-T\u7d30\u80de\u7642\u6cd5\u7684\u6210\u529f\u4fc3\u4f7f\u5168\u7403\u8840\u6db2\u548c\u975e\u8840\u6db2\u7cfb\u7d71\u60e1\u6027\u816b\u7624\u7684CAR-T\u81e8\u5e8a\u8a66\u9a57\u51fa\u73fe\u5feb\u901f\u589e\u9577\u3002 <\/p>\n

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\u9996\u4f4d\u63a5\u53d7CAR-T\u6cbb\u7642\u7684\u665a\u671f\u767d\u8840\u75c5\u764c\u75c7\u60a3\u8005\u7372\u5f97\u9577\u9054\u5341\u5e74\u7684\u7de9\u89e3\u671f\u3002 Nature 2022<\/i><\/span><\/strong><\/h3>\n
\n
\u76ee\u524d\uff0c\u9999\u6e2f\u60a3\u8005\u9700\u8981\u524d\u5f80\u7f8e\u570b\u6216\u5176\u4ed6\u6d77\u5916\u5730\u9ede\u9032\u884cCAR-T\u7d30\u80de\u6cbb\u7642\uff0c\u6216\u8005\u9700\u8981\u51b7\u51cd\u60a3\u8005\u8840\u6db2\uff0c\u904b\u5f80\u6d77\u5916\u9032\u884cCAR-T\u7d30\u80de\u751f\u7522\uff08\u6210\u672c\u7d0440\u842c\u7f8e\u5143\uff09\uff0c\u5b8c\u6210\u88fd\u9020\u548c\u57f9\u990a\uff0c\u51b7\u51cdCAR-T\u7d30\u80de\uff0c\u904b\u56de\u9999\u6e2f\uff0c\u7d93\u89e3\u51cd\u5f8c\u624d\u80fd\u9032\u884c\u6cbb\u7642\u3002\u6b64\u5197\u9577\u7684\u751f\u7522\u6d41\u7a0b\u6703\u5f71\u97ff\u6cbb\u7642\u6642\u6a5f\u548c\u6cbb\u7642\u6548\u679c\u3002\u75c5\u4eba\u751a\u81f3\u6709\u53ef\u80fd\u5728\u7b49\u5f85\u7522\u54c1\u751f\u7522\u53ca\u904b\u8f38\u671f\u9593\u96e2\u4e16\u3002 <\/div>\n<\/div>\n

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\u6b64\u524d\u9999\u6e2f\u5c1a\u7121\u7372\u5f97\u6279\u51c6\u6216\u7b26\u5408\u8cc7\u683c\u7684CAR-T\u751f\u7522\u8a2d\u65bd<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

> 400,000<\/span><\/strong>
\u9999\u6e2f\u764c\u75c7\u60a3\u8005\u6578 <\/p>\n

~ 35,000<\/span><\/strong>
\u9999\u6e2f\u6bcf\u5e74\u65b0\u589e\u764c\u75c7\u60a3\u8005\u4eba\u6578 <\/p>\n

750\u842c vs 8600\u842c<\/span><\/strong>
\u9999\u6e2f\u4eba\u53e3 vs \u7cb5\u6e2f\u6fb3\u5927\u7063\u5340\u4eba\u53e3<\/p>\n

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\u512a\u57fa\u79d1\u6280\u7684CAR-T\u7d30\u80de\u751f\u7522\u5e73\u53f0\u5177\u6709\u9ad8\u5ea6\u7684\u9748\u6d3b\u6027\u548c\u53ef\u64f4\u5c55\u6027<\/span><\/p>\n

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CAR-T\u7642\u6cd5\u6700\u8fd1\u7684\u6210\u529f\u4fc3\u4f7f\u5168\u7403\u91dd\u5c0d\u8840\u6db2\u816b\u7624\u3001\u5176\u4ed6\u60e1\u6027\u816b\u7624\u548c\u5be6\u9ad4\u7624\u7684CAR-T\u81e8\u5e8a\u8a66\u9a57\u6578\u91cf\u5feb\u901f\u589e\u9577\u3002\u70ba\u4e86\u751f\u7522CAR-T\u7d30\u80de\uff0c\u9700\u8981\u5f9e\u60a3\u8005\u81ea\u8eab\u7684\u8840\u6db2\u4e2d\u5206\u96e2\u51faT\u7d30\u80de\uff0c\u4e26\u901a\u904e\u57fa\u56e0\u5de5\u7a0b\u6539\u9020\u4f7f\u5176\u8868\u9054\u5d4c\u5408\u6297\u539f\u53d7\u9ad4\uff08CAR\uff09\uff0c\u4ee5\u8b58\u5225\u7279\u5b9a\u7684\u764c\u7d30\u80de\u6297\u539f\u3002\u7136\u5f8c\u901a\u904e\u8f38\u6db2\u5c07CAR-T\u7d30\u80de\u56de\u8f38\u81f3\u60a3\u8005\u9ad4\u5167\uff0c\u5f9e\u800c\u6709\u6548\u5730\u9776\u5411\u4e26\u7834\u58de\u764c\u7d30\u80de\u3002<\/p>\n

CAR-T\u7d30\u80de\u7684\u751f\u7522\u904e\u7a0b\u9700\u8981\u5728\u7b26\u5408cGMP\u6a19\u6e96\u7684\u751f\u7522\u57fa\u5730\u4e2d\u5b8c\u6210\u3002\u6b64cGMP\u6a19\u6e96\u5df2\u7372\u5f97\u7f8e\u570b\u98df\u7269\u53ca\u85e5\u7269\u7ba1\u7406\u5c40\uff08USFDA\uff09\u3001\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u548c\u9999\u6e2f\u885b\u751f\u7f72\uff08HK\u2019s Department of Health\uff09\u7b49\u85e5\u7269\u76e3\u7ba1\u6a5f\u6784\u7684\u6279\u51c6\u3002\u512a\u57fa\u662f\u9999\u6e2f\u9996\u5bb6\u751f\u7522CAR-T\u7d30\u80de\u7684cGMP\u751f\u7522\u57fa\u5730\uff0c\u7d50\u5408\u6211\u5011\u7684\u5408\u4f5c\u5925\u4f34Miltenyi Biotec\u958b\u767c\u7684CliniMAC Prodigy\u5e73\u53f0\uff0c\u6211\u5011\u4ee5\u81ea\u52d5\u5316\u548c\u6a19\u6e96\u5316\u7684\u6d41\u7a0b\u751f\u7522CAR-T\u7522\u54c1\uff0c\u4f7f\u9019\u7a2e\u6700\u65b0\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\u80fd\u591f\u5f97\u5230\u666e\u53ca\u3002\u4f7f\u7528\u6211\u5011CAR-T\u7522\u54c1\u7684\u6a5f\u6784\u5305\u62ec\u746a\u9e97\u91ab\u9662\u5152\u79d1\u548c\u9752\u5c11\u5e74\u91ab\u5b78\u79d1\u4ee5\u53ca\u9999\u6e2f\u5152\u7ae5\u91ab\u9662\u3002<\/p>\n

\u5982\u679c\u60a8\u5c0dCAR-T\u7d30\u80de\u6cbb\u7642\u611f\u8208\u8da3\uff0c\u8acb\u806f\u7e6b\u60a8\u7684\u816b\u7624\u79d1\u91ab\u751f\u6216\u6211\u5011\u7684\u5c08\u5bb6\u3002<\/p>\n

[\/et_pb_text][et_pb_image src=”https:\/\/www.xelleratherapeutics.com\/wp-content\/uploads\/2024\/10\/Xellera-Cancer-gene-therapy-tradcn-new-1200×43-1.jpg” alt=”Xellera-Cancer-gene-therapy” title_text=”Xellera-Cancer-gene-therapy-tradcn-new-1200×43″ _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_button button_url=”\/zh-hant\/\u806f\u7e6b\u6211\u5011\/#contact” button_text=”\u806f\u7d61\u6211\u5011\u7684\u5c08\u5bb6” button_alignment=”center” _builder_version=”4.14.8″ _module_preset=”default” custom_button=”on” button_bg_color=”#FFFFFF” button_border_radius=”40px” button_icon=”||divi||400″ button_icon_color=”#FFFFFF” locked=”off” global_colors_info=”{}” button_bg_color__hover_enabled=”on|desktop” button_text_color__hover_enabled=”on|hover” button_text_color__hover=”#FFFFFF” button_bg_color__hover=”#c13447″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Clinical-grade iPSC manufacturing
\n” module_id=”iPSCs” _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.8″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.8″ _module_preset=”default” text_orientation=”justified” global_colors_info=”{}”]<\/p>\n

iPSC\u7d30\u80de\u5eab<\/h1>\n

[\/et_pb_text][et_pb_text _builder_version=”4.14.8″ _module_preset=”default” text_orientation=”justified” global_colors_info=”{}”]\u8a98\u5c0e\u6027\u591a\u529f\u80fd\u5e79\u7d30\u80de\uff08iPSC\uff09\u53ef\u4ee5\u5206\u5316\u57f9\u990a\u6210\u6240\u6709\u7d30\u80de\u985e\u578b\uff0c\u5305\u62ec\u4e0d\u53ef\u518d\u751f\u7684\u5fc3\u81df\u7d30\u80de\u548c\u8166\u7d30\u80de\uff0c\u4e3b\u8981\u7528\u65bc\u91cd\u5efa\u6216\u4fee\u5fa9\u53d7\u640d\u5668\u5b98\u6216\u7d44\u7e54\u3002\u57fa\u65bciPSC\u7684\u514d\u75ab\u7642\u6cd5\u4e5f\u6b63\u5728\u958b\u767c\u4e2d\uff0c\u7528\u65bc\u6cbb\u7642\u4e0d\u540c\u7684\u764c\u75c7\u985e\u578b\u3002\u56e0\u6b64\uff0ciPSC\u4f5c\u7232\u201c\u539f\u6750\u6599\u201d\u662f\u7d30\u80de\u7642\u6cd5\u4e0d\u53ef\u6216\u7f3a\u7684\u4e00\u90e8\u5206\u3002\u8207\u5668\u5b98\u79fb\u690d\u985e\u4f3c\uff0c\u95dc\u9375\u8003\u616e\u56e0\u7d20\u662f\u514b\u670d\u7531\u65bc\u4f9b\u9ad4\u548c\u53d7\u9ad4\u4e0d\u540c\u800c\u5c0e\u81f4\u7684\u514d\u75ab\u6392\u65a5\u53cd\u61c9\uff0c\u9019\u7a81\u51fa\u4e86iPSC\u7d30\u80de\u5eab\u7684\u91cd\u8981\u6027\uff0c iPSC \u7d30\u80de\u5eab\u662f\u6e90\u81ea\u4eba\u7fa4\u4e2d\u6700\u5e38\u898b\u55ae\u500d\u578b\u7d14\u5408\u5b50\uff08homozygous haplotypes\uff09\u500b\u9ad4\uff0c\u4ee5\u5339\u914d\u4eba\u985e\u767d\u7d30\u80de\u6297\u539f\uff08HLA\uff09\u7cfb\u7d71\uff0c\u8a72\u7cfb\u7d71\u7de8\u78bc\u7d30\u80de\u8868\u9762\u5206\u5b50\u5c08\u9580\u7528\u65bc\u5c07\u6297\u539f\u80bd\u5448\u905e\u7d66T\u7d30\u80de\u4e0a\u7684\u53d7\u9ad4\u3002iPSC\u7d30\u80de\u5eab\u7684\u5efa\u7acb\u53ef\u4ee5\u63d0\u4f9b\u73fe\u6210\u7684iPSC\uff0c\u9019\u4e9biPSC\u8207\u9700\u8981\u7d30\u80de\u7642\u6cd5\u7684\u500b\u9ad4\u60a3\u8005\u5bc6\u5207\u5339\u914d\u3002
\n[\/et_pb_text][et_pb_image src=”https:\/\/www.xelleratherapeutics.com\/wp-content\/uploads\/2024\/10\/iPSC-haplobank-tradcn-new-1012×693-1.jpg” alt=”iPSC-haplobank” title_text=”iPSC-haplobank-tradcn-new-1012×693″ _builder_version=”4.14.8″ _module_preset=”default” locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.14.8″ _module_preset=”default” text_orientation=”justified” global_colors_info=”{}”]<\/p>\n

\u4e16\u754c\u5404\u5730\u5df2\u7d93\u5efa\u7acb\u4e86\u8a31\u591aiPSC\u7d30\u80de\u5eab\uff0c\u5305\u62ec\u7f8e\u570b\u3001\u65e5\u672c\u548c\u97d3\u570b\u3002\u512a\u57fa\u8207\u9999\u6e2f\u7d05\u5341\u5b57\u6703\u8f38\u8840\u670d\u52d9\u4e2d\u5fc3\u3001\u9999\u6e2f\u5927\u5b78\u746a\u9e97\u91ab\u9662\u3001\u8607\u683c\u862d\u570b\u5bb6\u8f38\u8840\u670d\u52d9\u4e2d\u5fc3\u548c\u611b\u4e01\u5821\u5927\u5b78\u7b49\u672c\u5730\u548c\u6d77\u5916\u6a5f\u69cb\u5408\u4f5c\uff0c\u5728\u9999\u6e2f\u555f\u52d5\u4e86\u7b2c\u4e00\u500biPSC\u7d30\u80de\u5eab\u9805\u76ee\u3002 <\/p>\n

The Global Alliance for iPSC Therapies\u662f\u4e00\u500b\u7d44\u7e54\u806f\u76df\uff0c\u5305\u62ecNew York Stem Cell Foundation <\/a>(New York, USA) \uff0cthe Cell and Gene Therapy Catapult <\/a>(London, UK) \uff0cthe Centre for Commercial-ization of Regenerative Medicine<\/a> (Toronto, Canada) \uff0cthe Korean HLA-Typed iPSC Banking Initiative (Seoul, Korea) \uff0cthe French Institute of Health and Medical Research<\/a> INSERM\uff08Paris\uff0cFrance\uff09\u548c\u9999\u6e2f\u5927\u5b78\uff08\u4e2d\u570b\u9999\u6e2f\uff09\uff0c\u5176\u76ee\u7684\u662f\u652f\u6301\u8a98\u5c0e\u6027\u591a\u529f\u80fd\u5e79\u7d30\u80de\u7642\u6cd5\u7684\u5be6\u65bd\u548c\u81e8\u5e8a\u61c9\u7528\uff0c\u4ee5\u9020\u798f\u5168\u7403\u60a3\u8005\u3002\u6709\u95dcGAiT\u7684\u66f4\u591a\u8cc7\u8a0a\uff0c\u8acb\u53c3\u95b1\u6700\u8fd1\u767c\u8868\u7684\u6587\u7ae0<\/a>\u3002 <\/p>\n

\u4f5c\u70baGAiT\u7684\u6210\u54e1\u5730\u5340\uff0c\u512a\u57fa\u7684iPSC\u7684\u751f\u7522\u65b9\u6cd5\u7b26\u5408GAiT\u6307\u5f15\u3002\u6211\u5011\u7684iPSC\u751f\u7522\u6d41\u7a0b\u7b26\u5408FDA\u3001EMA\u548cPIC\/S\u88fd\u5b9a\u7684\u76e3\u7ba1\u6307\u5f15\u3002\u806f\u7e6b\u6211\u5011\uff0c\u9032\u4e00\u6b65\u77ad\u89e3iPSC\u7d30\u80de\u5eab\u7684\u66f4\u591a\u8a73\u7d30\u8cc7\u8a0a\u3002 <\/p>\n

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Others<\/h1>\n

[\/et_pb_text][et_pb_text _builder_version=”4.14.8″ _module_preset=”default” text_orientation=”justified” global_colors_info=”{}”]Coming Soon
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